≥99%
Tesamorelin + Ipamorelin Blend
A reference blend of a GHRH analog and a selective GHS-R1a secretagogue, supplied as a lyophilized standard for in-vitro receptor-binding and co-incubation assay research. Not for use in any living organism.
1 vial × $100 each
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Third-party tested
Supplied to qualified labs and institutional buyers. Institutional use & buyer eligibility
Characteristics
| Property | Value |
|---|---|
| Components | Tesamorelin (modified GHRH 1-44) + Ipamorelin |
| Tesamorelin Molecular Formula | C₂₂₁H₃₆₆N₇₂O₆₇S |
| Ipamorelin Molecular Formula | C₃₈H₄₉N₉O₅ |
| Tesamorelin Molar Mass | 5135.89 g/mol |
| Ipamorelin Molar Mass | 711.85 g/mol |
| Physical Form | Lyophilized powder blend |
| Solubility | Both components soluble in aqueous buffer; reconstitute for in-vitro laboratory use only |
| Organoleptic Profile | White to off-white lyophilized powder; odorless |
| Storage Conditions | Store lyophilized at 2-8°C; use reconstituted solution promptly |
| Composition | Lyophilized blend of Tesamorelin acetate and Ipamorelin acetate |
How is Tesamorelin + Ipamorelin Blend Used in Research?
The Tesamorelin + Ipamorelin blend is a lyophilized research formulation combining a 44-amino acid modified GHRH analog (5135.89 g/mol) and a 5-amino acid synthetic pentapeptide (711.85 g/mol) for in-vitro two-receptor co-activation studies. Supplied as a laboratory research standard. Not for use in any living organism.
Characterization workflows profile the blend in recombinant GHRH-R and GHS-R1a expression systems in parallel. Standard readouts include cAMP accumulation (Gs-cAMP-PKA pathway) and IP1/calcium-flux panels (Gq/11-PLC-calcium pathway). The blend is used as a combined reference mixture for functional characterization of the two-receptor system.
Researchers use this blend for analytical method development (HPLC/LC-MS comparability assays requiring simultaneous quantitation of both peptides) and as a two-component reference standard in competitive-binding and receptor-selectivity profiling workflows.
This product is supplied in a lyophilized form and requires reconstitution prior to laboratory handling. For research and laboratory use only. Not for human or veterinary consumption.
Areas of Study
Two-Receptor In-Vitro Co-Activation Studies
Applied as a combined reference mixture for parallel GHRH-R and GHS-R1a binding and functional readouts.
Receptor Selectivity Profiling
Used in multi-receptor competitive-binding panels to profile each component's selectivity signature.
Analytical Method Development
Serves as a combined identity and purity reference standard in HPLC and LC-MS comparability workflows.
Structural Characterization
Profiled by mass spectrometry and circular dichroism to confirm sequence identity and secondary-structure content of both components.
In-Vitro Functional Panels
Used as a two-component reference in cAMP accumulation and calcium-flux cell-based assays.
References
- [1]Ferdinando C, Bowers CY. (2010). Growth hormone-releasing hormone analogs: pharmacology and preclinical metabolic effects. Growth Hormone & IGF Research, 20(3), 186-193.
- [2]Raun K, Hansen BS, Johansen NL, et al. (1998). Ipamorelin, the first selective growth hormone secretagogue. European Journal of Endocrinology, 139(5), 552-561.
- [3]Bowers CY, Granda R, Mohan S, et al. (2004). Sustained elevation of pulsatile growth hormone (GH) secretion and insulin-like growth factor I (IGF-I). Journal of Clinical Endocrinology & Metabolism, 89(10), 5174-5181.
- [4]Gaylinn BD, Thorner MO. (2001). GHRH receptors and GH secretion. Growth Hormone & IGF Research, 11(Suppl A), S35-S38.
Disclaimer: The information provided is for research reference only and does not constitute medical advice. Products are sold strictly for in-vitro research use.
Certificate of Analysis (COA)
Third-Party Verified Quality
Every batch of Tesamorelin + Ipamorelin Blendis independently tested by an A2LA-accredited (ISO 17025:2017) third-party laboratory using HPLC-UV/VIS for purity and measured quantity. Each COA carries the lab's signed report and a batch-specific lot number. We publish these results publicly so you can verify exactly what you're getting.
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